STREPTOCOCCI 2026 Conference Report

Global Virtual Conference on Streptococcus Research Symposium

Date: April 27–28, 2026 | Format: Virtual (EDT)
Organized by: Impact Research Communications

The 2026 Global Virtual Streptococcus Research Symposium brought together leading microbiologists, immunologists, and clinicians to advance understanding of Streptococcus pathogenesis, immunity, and clinical outcomes. Over two days, the symposium highlighted breakthroughs in host-pathogen crosstalk, immune evasion, biofilm biology, and antimicrobial resistance—underscoring the urgent need for innovation in tackling streptococcal diseases worldwide.

Day 1: Host-Pathogen Interactions & Immune Responses

Session I: Molecular Crosstalk & Autoimmunity

  • Dr. Francis J. Castellino (USA) examined host-pathogen molecular interactions in Group A Streptococcus infections.
  • Dr. Madeleine W. Cunningham (USA) explored autoimmune mechanisms underlying rheumatic fever and PANDAS.
  • Dr. Debra E. Bessen (USA) presented longitudinal data on Strep A-specific IgG in school-aged children.
  • Dr. Giuseppe Teti (Italy) discussed innate immunity shaped by streptococcal exposure.
  • Dr. Caroline Weight (UK) highlighted respiratory epithelial activation during S. pneumoniae infection.

Session II: Immune Evasion & Protective Responses

  • Dr. Nikolai Siemens (Germany) described host defense interplay with pathogen evasion in S. pyogenes.
  • Dr. H. Alexandra Shaw (UK) introduced a standardized serum for Strep A research.
  • Dr. Christopher LaRock (USA) detailed innate immune sensing of streptococcal proteases.
  • Dr. Alexander J. Keeley (UK) analyzed M-type specific antibody responses in protective immunity.

Session III: Inflammatory Signaling & Pathophysiology

  • Dr. Rebecca Flaherty (USA) investigated macrophage death and inflammatory signaling in Group B Streptococcus.
  • Dr. Samuel Shelburne (USA) revealed CovRS system impacts on GAS pathophysiology.
  • Dr. Guangchun Bai (USA) presented on cyclic di-AMP regulation in S. pneumoniae virulence and competence.

Day 1 concluded with remarks emphasizing the integration of molecular immunology with translational research.

Day 2: Relapse, Biofilms & Antimicrobial Resistance

Session IV: Relapse & Colonization Dynamics

  • Dr. Timothy Barnett (Australia) provided insights into relapse infections in Group A Streptococcus.
  • Dr. Justin Zik (Singapore) applied dual transposon sequencing to map bacterial genetic interactions.
  • Dr. Sven Hammerschmidt (Germany) examined pneumococcal cross-talk at colonization and invasive disease boundaries.
  • Dr. Shaynoor Dramsi (France) studied S.gallolyticus interactions with human colonic mucus.

Session V: Biofilms & Genetic Susceptibility

  • Dr. Marcus Fulde (Germany) discussed host-pathogen dynamics in Streptococcus canis.
  • Ms. Diana Pohlman (USA) presented efforts to build a genetic susceptibility repository for PANDAS and Sydenham chorea.
  • Dr. Pratyush Madapuji Ravi (USA) highlighted high-throughput imaging assays for S. pneumoniae biofilm lifecycle genes.

Session VI: Vaccines, Resistance & Clinical Perspectives

  • Dr. Eileen M. Dunne (USA) reported on pneumococcal conjugate vaccine effectiveness.
  • Dr. Andrew Fenton (UK) addressed strategies to overcome penicillin resistance in S. pneumoniae.
  • Dr. Laia Pasquina Lemonche (UK) used AFM imaging to reveal antibiotic-induced cell wall damage.
  • Dr. Slawomir Lukomski (USA) discussed invasive emm92-type GAS infections and MLSB resistance.
  • Dr. Saugata Majumder (USA) demonstrated enhanced lung-resident immunity via intranasal PspA boosting.
  • Dr. Stephanie S. Momeni (USA) advanced perspectives on S. mutans in early childhood dental caries.

The symposium closed with remarks highlighting the convergence of immunology, genomics, and clinical research in advancing streptococcal disease management.

Global Participation

Countries represented included: USA, UK, Germany, Italy, France, Australia, Singapore, and others—reflecting the international scope of streptococcal research and clinical collaboration.

Key Takeaways

  • Host-pathogen crosstalk: Molecular and immune interactions drive both protection and pathology in streptococcal infections.
  • Immunity & autoimmunity: Advances in understanding autoimmune sequelae (rheumatic fever, PANDAS) highlight the complexity of host responses.
  • Biofilm biology: Novel imaging and genetic tools are uncovering biofilm lifecycle regulation in S. pneumoniae.
  • Antimicrobial resistance: Emerging resistance mechanisms demand innovative therapeutic strategies.
  • Global collaboration: The symposium reaffirmed the collective commitment to tackling streptococcal diseases through interdisciplinary science and innovation.